CYKLOKAPRON Filmtabl 500 mg (Tranexamsäure): Antifibrinolytikum, Aminosäure; Blister 30 Stk: Liste B, SL: 10%, CHF 26.10. . Do not take it for more than the prescribed dose. After first opening: the solution for injection/infusion is for single use only. Licence Number PA2010/055/001. - Thoracic and abdominal surgery and other major surgical intervention such as cardiovascular surgery. Immediately before tooth extraction in patients with hemophilia, administer 10 mg per kg body weight of CYKLOKAPRON intravenously together with replacement therapy (see PRECAUTIONS). The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. Tranexamic acid is indicated in adults and children from one year in prevention and treatment of haemorrhages due to general or local fibrinolysis. SIDE EFFECTS: Nausea, vomiting, diarrhea, or dizziness may occur. 1 Filmtablette enthält 500 mg Tranexamsäure. Simultaneous treatment with anticoagulants must take place under the strict supervision of a physician experienced in this field. Zur Anwendung bei Kindern und Erwachsenen. . it may cause stomach ache; it may cause muscle pain; Each person may react differently to a treatment. If you think this medication may be causing side effects . If you forget a dose, take it as soon as you remember -- unless it is almost time for your next dose. If bleeding does not stop, contact your doctor, you may need further evaluation, The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. What is in this leaflet: 1. . Shelf lifetime is 24 Months. Hence, driving is not contraindicated if taking this medicine. Please try again. In coronary artery bypass graft (CABG) surgery, most of these cases were reported following intravenous (IV.) How to take Cyklokapron 4. %PDF-1.5
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Dosierung. 1. Für die derzeit zugelassenen Anwendungsgebiete liegt die Dosierung für Kinder im Bereich von 25 mg/kg pro Dosis. Print your most beautiful photos, thanks to our photo services. However, this does not rule out the possibility of interaction and it is better to avoid alcohol consumption. However, data on efficacy, posology and safety for these indications are limited. Cyklokapron: L'acide tranexamique appartient à la classe de médicaments appelés agents antifibrinolytiques. You should take this medicine regularly, at the same time and w, The effect of Cyklokapron will be reduced if taken along with blood thinners (like warfarin, heparin) which are medicines that inhibit clot formations, An additive effect may be seen if the patient is taking medications that increase blood clot formation (like aprotinin), Oral contraceptive pills, when taken with Pause, may promote blood clot formation which can be harmful, leading to blockage of blood vessels by abnormal clot formation. 1.36 to 2.83 (120 to 250 micromol/L) 10 mg/kg twice daily: 2.83 to 5.66 (250 to 500 micromol/L) 10 mg/kg daily >5.66 (>500 micromol/L) 10 mg/kg every 48 hours or 5 mg/kg every 24 hours 1 Brausetabl. You should not consume it more than that prescribed by your doctor. PRECAUTIONS: Before taking tranexamic acid, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Tranexamic acid should be used throughout pregnancy only if the expected benefit justifies the potential risk. See additional information. Packs with 10 x 1 Type I glass 5 mL ampoules in an outer carton, each ampoule containing 500 mg tranexamic acid. endstream
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Consumer information about the medication TRANEXAMIC ACID 500 MILLIGRAM TABLET - ORAL (Cyklokapron), includes side effects, drug interactions, recommended dosages, and storage information. With continuous long-term use of tranexamic acid, regular ophthalmologic examinations (eye examinations including visual acuity, colour vision, fundus, visual field etc.) Symptoms of overdose may include: severe dizziness, vomiting. . ithout fail as directed by your doctor. Cyklokapron-Injektionslösung. In Tablettenform ist er geeignet zur Vorbeugung und Behandlung bei. Cyklokapron® 500 mg 20 St für nur € 27,51 bei Ihrer Online Apotheke für Deutschland kaufen und bis zu 6% sparen. Pharmacological properties. Intrathecal and intraventricular injection, intracerebral application (risk of cerebral oedema and convulsions). A: You should take Cyklokapron in the exact dose and frequency prescribed by the doctor. Take it for as long as the doctor has told you to take it. However, one should watch out for signs of blurring of vision or loss of colour vision which may appear as a side effect of this medication. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug include: "blood thinners" (anticoagulants such as warfarin, heparin), drugs that prevent bleeding (including factor IX complex, anti-inhibitor coagulant concentrates, aminocaproic acid), estrogens, hormonal birth control (such as pills, patch, ring).Check all prescription and nonprescription medicine labels carefully since many medications contain pain relievers/fever reducers (NSAIDs such as aspirin, ibuprofen, naproxen) that may increase your risk of bleeding. Packungen mit 5, 6 oder 10 Typ-I-Glasampullen zu 5 ml mit je 500 mg Tranexamsäure im Umkarton. From a microbiological point of view, the product should be used immediately. It is also used in people with other high-risk bleeding conditions to control bleeding at such times as after surgery or an injury, during heavy nosebleeds, or during heavy menstrual bleeding . A: No, it is usually prescribed for a short duration. Signs and symptoms may include dizziness, headache, hypotension, and convulsions. US residents can call their local poison control center at 1-800-222-1222. • In this leaflet, Cyklokapron 500 mg film-coated tablets will be called Cyklokapron. Serum Creatinine (mg/dL) CYKLOKAPRON Intravenous Dosage * Dose reduction is recommended for all doses, both before and after tooth extraction. Trade Name Cyklokapron 500 mg Film-coated Tablets. The plasma protein binding of tranexamic acid is about 3% at therapeutic plasma levels and seems to be fully accounted for by its binding to plasminogen. This medication is typically used 3 times a day. Hence, it helps to stop excessive bleeding. Many people using this medication do not have serious side effects.Tell your doctor right away if you have any serious side effects, including: eye/eyelid problems.Although unlikely, this medication may cause serious blood clot problems and vision changes. The name of your medicine is Cyklokapron 500 mg film-coated tablets, which will be called Cyklokapron tablets throughout this leaflet. What is in this leaflet: 1. The initial volume of distribution is about 9 to 12 litres. Hereditary Angioedema (Off-label) Long-term prophylaxis: 1000-1500 mg PO q8-12hr; reduce dose to 500 mg/dose PO qDay or q12hr when frequency of attacks reduces. - Haemorrhage caused by general or local fibrinolysis such as: - Haemorrhagic urinary disorders, further to prostate surgery or surgical procedures affecting the urinary tract. Cyklokapron 500mg Injection helps prevent or reduce heavy bleeding post surgery and in conditions such as heavy periods, dysfunctional uterine bleeding, and nosebleeds. What Cyklokapron is and what it is used for 2. Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. In patients with a history of thromboembolic diseases or in those with increased incidence of thromboembolic events in their family history (patients with a high risk of thrombophilia), tranexamic acid should only be administered if there is a strong medical indication after consulting a physician experienced in haemostaseology and under strict medical supervision (see section 4.3). Tranexamsäure Carino 100 mg/ml Injektionslösung. . Do not use more of this product, or more often, than prescribed. If you missed any dose of medicine take it as soon as you remember. Tranexamic acid does not bind to serum albumin. Take advantage of the personalized services offered online and in pharmacies to take charge of your health and take better care of yourself. You need to properly discard this medicine when it is expired or no longer needed. Can I drive if I have consumed Cyklokapron? Following administration of an intravenous injection of 10 mg/kg to 17 patients undergoing knee surgery, concentrations in the joint fluids were similar to those seen in corresponding serum samples. "��O|��]���k%���t�p�����h��h������IX��L��`��@i@�����Ht��2�*�&�>�P���$��B �܈��e�U�Je�k��5����ķ��6"'E�#�Gy In case of haematuria from the upper urinary tract, there is a risk for urethral obstruction. This medicine should be taken as directed by the doctor and in doses and duration as prescribed. Side effects. 15 mg/kg body weight twice daily. If not used immediately, in-use storage times and conditions prior to use are the responsibility of the user. Tranex, Take Cyklokapron Tablet as told by your doctor with a sufficient amount of water, and swallowed whole. Pharmacotherapeutic group: Antihaemorrhagics, Antifibrinolytics, Amin oacids. Information last revised March 2014. Missing a dose of Cyklokapron Tablet may reduce the effectiveness of the treatment. Keep this medicine away from children and pets. Tranexamic acid diffuses rapidly into joint fluid and the synovial membrane. Tranexamic acid. Beipackzetteln.de . Do not double the next dose to catch up. Nonmedicinal ingredients: cellulose microcrystalline, colloidal silica anhydrous, hydroxypropylcel, magnesium stearate, povidone, talcum. Its effects can be noticed within a few hours. 1.36 to 2.83 (120 to 250 micromol/L) 10 mg/kg twice daily: 2.83 to 5.66 (250 to 500 micromol/L) 10 mg/kg daily >5.66 (>500 micromol/L) 10 mg/kg every 48 hours or 5 mg/kg every 24 hours Consult your doctor before breast-feeding. We strive to grow while continuing to improve our products and services through our 140 affiliated Brunet, Brunet Plus and Brunet Clinique pharmaceutical establishments and 3,000 employees. Most of them were controlled versus placebo. Gebrauchsinformation zum Cyklokapron 500 mg, alle Informationen einschließlich Dosierung, Nebenwirkungen, Preisvergleich usw. In that case, skip the missed dose. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.MEDICAL ALERT: Your condition can cause complications in a medical emergency. Check more medicines with composition as Tranexamic Acid (500.0 Mg) View. MISSED DOSE: If you miss a dose, take it as soon as you remember. Tranexamic acid passes through the placenta. Within each system organ class, adverse reactions are ranked by frequency. NDA 19-281 . However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. 500 mg Tranexamsäure - Die . blood vessels in the brain, blood clots in vessels of the lower limbs etc. Read more about the prescription drug TRANEXAMIC ACID 500 MILLIGRAM TABLET - ORAL. The most adapted dosing schedule appeared to be: - first bolus of 10 mg/kg after induction of anaesthesia and prior to skin incision. Sorry, an unexpected error occurred. 2-3 Tabl. This document does not contain all possible drug interactions. %%EOF
HOW TO USE: Take this medication by mouth, usually 2 to 4 times daily or as directed by your doctor.The dosage and length of treatment is based on your medical condition and response to treatment. Die empfohlene Dosierung beträgt 3 bis 4 x täglich 2-3 Filmtabletten, für 3 bis 4 Tage. Erwachsene Erhöhte lokale Fibrinolyse: übliche Dosierung: 2-3×tgl. Intravenous administration of 10 mg per kg body weight gave plasma concentrations of 18.3 μg, - continuous infusion of 10 mg/kg/h or injection into the CPB pump prime at a dose adapted on the CPB procedure, either according to a patient weight with a dose of 10 mg/kg dose, either according to CPB pump prime volume, last injection of 10 mg/kg at the end of CPB. 1.36 to 2.83 (120 to 250 micromol/L) 10 mg/kg twice daily: 2.83 to 5.66 (250 to 500 micromol/L) 10 mg/kg daily >5.66 (>500 micromol/L) 10 mg/kg every 48 hours or 5 mg/kg every 24 hours You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. Do not exceed the prescribed duration. These side effects normally go away with time, but if you feel the side effects persist, you should consult your doctor. Serum Creatinine (mg/dL) Cyklokapron Intravenous Dosage * Dose reduction is recommended for all doses, both before and after tooth extraction. >500 (>5.66 mg/dL) or . It is not intended, in any way, to replace the advice of a trained health professional. oder 2-4×tgl. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Severe renal impairment (risk of accumulation). Contents of the pack and other information. Ask your doctor or pharmacist for more details. Adverse reactions are listed according to MedDRA primary system organ class. Do not double the dose to catch up. Injektionslösung. Cyklokapron-Injektionslösung ist eine klare, farblose Lösung in einer Typ-I-Ampulle aus Glas. Before using this medicine, consult your doctor or pharmacist if you have: current blood clots (e.g., in the legs, lungs, brain, eye), bleeding in the brain (subarachnoid hemorrhage), color vision problems.Before using this medication, tell your doctor or pharmacist your medical history, especially of: history of blood clots, a certain serious blood clotting problem (disseminated intravascular coagulation-DIC), kidney problems (including blood in the urine), irregular menstrual bleeding of unknown cause.This drug may make you dizzy. Before use of tranexamic acid, risk factors of thromboembolic disease should be considered. How to take Cyklokapron tablets 4. Do not crush or chew the Tablets. Injection: 1,000 mg tranexamic acid (100 mg/mL) clear and colorless solution in 10 mL single-dose ampules . There are no or limited amount of data from the use of tranexamic acid in pregnant women. ��J�=.��s. Clinical particulars. Cyklokapron 100mg/mL solution for injection/infusion. A: No, Cyklokapron is not intended to stop the period. Take advantage of discounts on select beauty products and get advice from cosmetics professionals. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Shelf lifetime is 3 Years. . Plasma concentrations increase in patients with renal failure. Possible side effects 5. Tranexamic Acid (500.0 Mg) Uses. Take it for the entire time prescribed in order to achieve the medication's full benefit. Father’s Day activity and gift ideas for every taste! Serum Creatinine (mg/dL) CYKLOKAPRON Intravenous Dosage * Dose reduction is recommended for all doses, both before and after tooth extraction. If you are allergic to tranexamic acid or any other ingredients of Cyklokapron Tablet. Renal clearance is equal to plasma clearance (110 to 116 mL/min). In vitro studies showed that high tranexamic dosages decreased the activity of complement. 5. Browse our current job openings for positions at our pharmacies, stores, and head office. genannte Therapie Cyklokapron Filmtabletten in einer Dosierung von 10-15 mg pro kg KG alle 8-12 Stunden in oraler Form gegeben werden. Hilfsstoffe. Alternatively, the antifibrinolytic action of the drug may be antagonised with thrombolytic drugs. 15 mg/kg body weight/day. Exclusive promos, answers to your questions and inspiration every day! zu starker Monatsblutung. Cyklokapron Tablet is used to stop bleeding in diseases or conditions that lead to excessive bleeding from the body, such as menses (periods), surgical procedure, nose bleed, internal bleeding. OVERDOSE: If overdose is suspected, contact a poison control center or emergency room immediately. factors II (prothrombin), VIII and X; increased plasma levels of fibrinogen degradation products; a normal platelet count. [Missing text '/GJC/shop/shoppingStoreSelectorModal/searchEmpty' for 'English']. You should not flush this medicine in the toilet or pour them into the drain. >5.66 (>500 micromol/L) 10 mg/kg every 48 hours or 5 mg/kg every 24 hours: 3 DOSAGE FORMS AND STRENGTHS. Cyklokapron side effects. Unless otherwise prescribed, the following doses are recommended: 1. �]C�������"ɖ�1��Y��֣�(��s\0��N�dž7�-ޚHkx����OG���؋까����yxՂR$A�3����p����34�b�Y���[�ٗ�Y��C��PBM>Y��j��bP��B|����MQ��Rh������w>��n�(�m�����}�g����"���x�ַ�N5VlQ���ӎ�p���Tlp��~��)�3K��96 k،��)$/:n����7�K�ٺL�wpd���x
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What you need to know before you take Cyklokapron tablets 3. Photo services: printing, photobooks, cards, etc. . Currently available data are limited and are described in section 5.1. If you have blood disorders known to increase blood clotting tendency. For patients with mild to moderate renal impairment, the dosage of tranexamic acid should be reduced according to the serum creatinine level: No dose adjustment is required in patient with hepatic impairment. Eg. In children from 1 year, for current approved indications as described in section 4.1, the dosage is in the region of 20 mg/kg/day. Within each frequency grouping, adverse reactions are presented in the order of decreasing seriousness. Limit alcoholic beverages.Kidney function declines as you grow older. Short term prophylaxis: 75 mg/kg/day PO divided q8-12hr for 5 days before and after the event. Tranexamic acid exerts an anti haemorrhagic activity by inhibiting the fibrinolytic properties of plasmin. Tranexamic acid is a structural analogue of an amino acid lysine which important for blood clotting process. With pathological ophthalmic changes, particularly with diseases of the retina, the physician must decide after consulting a specialist on the necessity for the long-term use of tranexamic acid in each individual case. Heparin may be added to Cyklokapron. Medicinal products that act on haemostasis should be given with caution to patients treated with tranexamic acid. h�bbd```b``��! hUmo�8�+��U��5q�VHJ��t�����!/��du���̄@��J��Sd����0�ϔ��2c`OL The indications and method of administration indicated above should be followed strictly: • Intravenous injections or infusions should be given very slowly (maximum 1 mL per minute). The ADRs reported from clinical studies and post-marketing experience are listed below according to system organ class. Women of childbearing potential have to use effective contraception during treatment. Studied population was heterogenic in terms of age, surgery types, dosing schedules. Heart attack or paralysis due to clot in. 2. GENERIC NAME: TRANEXAMIC ACID 500 MILLIGRAM TABLET - ORAL (TRAN-ex-AM-ik AS-id). It is given as a slow injection into a vein. Licence Holder Mylan IRE Healthcare Limited. The HPRA advises healthcare professionals not to retain printed versions of Summary of Product Characteristics (SPC) documents. When meeting with any health professional, it is important for you to share the following information: Medications and pharmaceutical services featured on brunet.ca are offered by Brunet’s affiliated pharmacist-owners. Try with different words or broader terms. Tranexamic acid should be administered with care in patients receiving oral contraceptives because of the increased risk of thrombosis (see section 4.5). 0
No reduction in dosage is necessary unless there is evidence of renal failure. For the full list of excipients, see section 6.1. Characteristically, the haematological profile approximates to the following: reduced euglobulin clot lysis time; prolonged prothrombin time; reduced plasma levels of fibrinogen, factors V and VIII, plasminogen fibrinolysin and alpha-2 macroglobulin; normal plasma levels of P and P complex; i.e. What you need to know before you take Cyklokapron 3. However, these symptoms resolve with time. Standard treatment of local fibrinolysis: 0.5 g (1 ampoule of 5 mL) to 1 g (1 ampoule of 10 mL or 2 ampoules of 5 mL) tranexamic acid by slow intravenous injection or infusion (= 1 mL/minute) two to three times daily. 2022 [cited 11 May 2022], LactMed. Filmtabletten. Cyklokapron 500 mg Filmtabletten. Cyklokapron 500 mg Filmtabletten enthalten den Wirkstoff Tranexamsäure. As with most medications, this product should be stored at room temperature. This Tablet works by preventing the breakdown of clots, thus further leading to the stoppage of bleeding. . Pharmaceutical form. You should not consume more than the recommended daily dose by the doctor. It is excreted mainly in the urine as unchanged drug. Non-clinical data reveal no special hazard for humans based on conventional studies of safety pharmacology, repeated dose toxicity, genotoxicity, carcinogenic potential, toxicity to reproduction and development. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. NOTES: Do not share this medication with others.Laboratory and/or medical tests (e.g., eye examinations) should be performed periodically to monitor your progress or check for side effects. All the Products are packed and stored Safely, Cyklokapron Tablet is used to treat and reduce excessive bleeding in menses (during periods), abnormal blood loss during or after a surgical procedure, bleeding from the nose known as epistaxis, to co. Important: Follow the instructions on the label. Tranexamic acid is excreted in human milk. Our aim is to provide Quebecers with personalized advice and services for their health and well-being. Dosage is also based on your weight. Make sure that any leftover portion is disposed of safely. Understanding and demystifying eating disorders. Report a suspected side effect or falsified product to the MHRA Yellow Card scheme. Bei sehr starken Monatsblutungen kann Ihr Arzt die Dosis erhöhen, die maximale Tagesdosis von 8 Filmtabletten darf nicht überschritten werden. The truth about cellulite and tips to reduce its appearance. Cyklokapron passes into human milk in a small amount, If a breastfeeding mother requires tranexamic acid, it is not a reason to discontinue breastfeeding. - Management of haemorrhage due to the administration of a fibrinolytic agent. If you think this medication may be causing side effects (including those described here, or others), talk to your health care professional. It is used in the treatment of uncontrollable bleeding conditions that are seen after tooth extraction, in menstruation, haemorrhage (the release of blood from a broken blood vessel), angioedema (painless swelling under the skin), etc. In addition to its desired action, this medication may cause some side effects, notably: Each person may react differently to a treatment. Keep all medicines away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. He or she can help you to determine whether or not the medication is the source of the problem. As these documents are subject to frequent content updates, including changes to safety and dose related information, we recommend that you visit our website as necessary to access the most up-to-date versions. 120-249. There are no clinical data on the effects of tranexamic acid on fertility. For storage conditions after first opening of the medicinal product, see section 6.3. Therapy. 2022 [cited 11 May 2022], Tranexamic acid - Medicine - NHS [Internet]. However, your pharmacist may have suggested a different schedule that is more appropriate for you. ��
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Please, Tranexamic acid - Summary of Product Characteristics (SmPC) - (emc) [Internet]. - Gynaecological surgery or disorders of obstetric origin. The administration is strictly limited to slow intravenous injection or infusion (see section 6.6) of maximum 1 mL per minute. Cases of convulsions have been reported in association with tranexamic acid treatment. There is no data regarding interactions between Cyklokapron and alcohol. Generally, a treatment with this medication lasts several days. Store it in a secure location where it will not be exposed to excessive heat, moisture or direct sunlight. Check out our promotions and get advice from a Brunet cosmetician. . The way to take this medicine is: Intravenous. Q: Should I take Cyklokapron with or without food? If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. � C�^A
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Diarrhoea, vomiting, nausea. Acute venous or arterial thrombosis (see section 4.4). This medicinal product should not be mixed with blood for transfusion or with solutions containing penicillin. Packungen mit 10 x 1 Typ-I-Glasampulle zu 5 ml mit je 500 mg . MedicineNet does not provide medical advice, diagnosis or treatment. HAEMOSTATICS. injection of tranexamic acid in high doses. As a result, although studies in animals do not indicate teratogenic effects, as precaution for use, tranexamic acid is not recommended during the first trimester of pregnancy. No interaction studies have been performed. Take this Tablet with food to avoid stomach upset. Missed DoseStorage. Excretion of tranexamic acid is about 90% within the first 24 hours after intravenous administration of 10 mg/kg body weight. Patients with disseminated intravascular coagulation (DIC) should in most cases not be treated with tranexamic acid (see section 4.3). Tranexamsäure hemmt zu starken Blutfluss, der durch durch mangelhafte Blutgerinnung verursacht wurde. Standard treatment of general fibrinolysis: 1 g (1 ampoule of 10 mL or 2 ampoules of 5 mL) tranexamic acid by slow intravenous injection or infusion (= 1 mL/minute) every 6 to 8 hours, equivalent to 15 mg/kg body weight (BW). Discuss the risks and benefits with your doctor.This drug passes into breast milk. Properly discard this product when it is expired or no longer needed. While studied in very few patients, the limited data suggest that continuous infusion is preferable, since it would maintain therapeutic plasma concentration throughout surgery. The activity of the tranexamic acid-plasmin complex on the activity on fibrin is lower than the activity of free plasmin alone. Cyklokapron does not directly affect alertness levels. 4.2 Dosierung und Art der Anwendung Dosierung Erwachsene Soweit nicht anders verordnet, gelten fol-gende Dosierungsempfehlungen: hU�n�@��s�*�wv����8U���M衲r��8��0��>T���삍�ʊ�3,3�����n�W�Il�����b(���Q
��!~�(��S���lp�G$]FX �9��&\I(���R�)ņ@����AW����M�r���$ For the full list of excipients, see section 6.1. This information is for use by healthcare professionals. are indicated. Any unused medicinal product or waste material should be disposed of in accordance with local requirements. Here are a few tips to help you find what you are looking for: This medication is typically used for a nosebleed or to stop bleeding following dental surgery. All content on brunet.ca is provided for informational purposes only.
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